Novel CuX2-mediated cyclization of acid-base salts of (L)-cinchonidine or (D)-/(L)-α-methylbenzylamine and 2,3-allenoic acids in an aqueous medium.: An efficient entry to optically active β-halobutenolides

被引：71

作者：

Ma, SM ^{[1
]}

Wu, SL ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, Organomet Chem Lab, Shanghai 200032, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2001年 / 05期

关键词：

D O I：

10.1039/b008818h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The treatment of 1:1 salts of 2,3-allenoic acid-chiral base with CuX2 (4 equiv.) in an aqueous medium, i.e. acetone-H2O (2:1), at 60-65 degreesC afforded beta -halobutenolides with high enantiopurities in good to excellent yields.

引用

页码：441 / 442

页数：2

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