A 2-way miRror of red blood cells and leukemia

被引：3

作者：

Grimes, H. Leighton ^{[1
]}

Meyer, Sara E. ^{[1
]}

机构：

[1] Cincinnati Childrens Hosp Med Ctr, Cincinnati, OH 45229 USA

来源：

BLOOD | 2015年 / 125卷 / 08期

关键词：

GATA1;

D O I：

10.1182/blood-2015-01-618975

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

In this issue of Blood, the articles by Shaham et al1 and Wang et al2 are the first to identify microRNA 486 (miR-486) as a requisite oncomiR and credible therapeutic target in myeloid leukemia of Down syndrome (ML-DS) and chronic myeloid leukemia (CML) by showing that these 2 leukemias co-opt miR-486 functions in normal erythroid progenitor progrowth and survival activity. © 2015 by The American Society of Hematology.

引用

页码：1202 / 1203

页数：4

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