Effects of a bolaamphiphile on the structure of phosphatidylcholine liposomes

被引:12
作者
Gu, Q
Zou, AH
Yuan, CW [1 ]
Guo, R
机构
[1] Southeast Univ, Minist Educ, Key Lab Mol & Biomol Elect, Nanjing 210096, Peoples R China
[2] Yangzhou Univ, Dept Chem, Yangzhou 225002, Peoples R China
基金
中国国家自然科学基金;
关键词
bolaamphiphile; PC liposomes; ultraviolet spectrum; zeta potential; membrane fluidity; micropolarity; micrograph; MLM; malachite green;
D O I
10.1016/S0021-9797(03)00649-0
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
This paper describes the morphological characterization of aqueous dispersions of PC amphiphiles and bolaamphiphile AEC by microscopy, the liposomal membrane fluidity, and the zeta potential. Results indicate that the bolaamphiphile AEC can be included within conventional egg-PC liposome bilayers. This behavior could be due to their preference for the stretched conformation within the PC membranes. (C) 2003 Elsevier Inc. All rights reserved.
引用
收藏
页码:442 / 447
页数:6
相关论文
共 35 条
[1]   THE INFLUENCE OF IONIC-STRENGTH AND LIPID BILAYER CHARGE ON THE STABILITY OF LIPOSOMES [J].
CARRION, FJ ;
DELAMAZA, A ;
PARRA, JL .
JOURNAL OF COLLOID AND INTERFACE SCIENCE, 1994, 164 (01) :78-87
[2]   Arenethiolate monolayer-protected gold clusters [J].
Chen, SW ;
Murray, RW .
LANGMUIR, 1999, 15 (03) :682-689
[3]  
DUYNSTEE EF, 1959, J AM CHEM SOC, V82, P4542
[4]   BOLAAMPHIPHILES - FROM GOLF BALLS TO FIBERS [J].
ESCAMILLA, GH ;
NEWKOME, GR .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1994, 33 (19) :1937-1940
[5]   FLUID AND SOLID FIBERS MADE OF LIPID MOLECULAR BILAYERS [J].
FUHRHOP, JH ;
HELFRICH, W .
CHEMICAL REVIEWS, 1993, 93 (04) :1565-1582
[6]   MOLECULAR MONOLAYER RODS AND TUBULES MADE OF ALPHA-(L-LYSINE),OMEGA-(AMINO) BOLAAMPHIPHILES [J].
FUHRHOP, JH ;
SPIROSKI, D ;
BOETTCHER, C .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1993, 115 (04) :1600-1601
[7]   BOLAAMPHIPHILES FORM ULTRATHIN, POROUS, AND UNSYMMETRIC MONOLAYER LIPID-MEMBRANES [J].
FUHRHOP, JH ;
FRITSCH, D .
ACCOUNTS OF CHEMICAL RESEARCH, 1986, 19 (05) :130-137
[8]  
FUHRHOP JH, 1994, MEMBRANES MOL ASSEMB
[9]  
GLIOZZI A, 1983, J MEMBRANE BIOL, V75, P45, DOI 10.1007/BF01870798
[10]  
GREGORIADIS G, 1993, LIPOSOME TECHNOLOGY, V1