Micro-synthesis and electron ionization mass spectral analysis of O-alkyl N,N-dialkylphosphoramidocyanidates

被引：14

作者：

Gupta, AK ^{[1
]}

Palit, M ^{[1
]}

Pardasani, D ^{[1
]}

Shakya, P ^{[1
]}

Srivastava, RK ^{[1
]}

Dubey, DK ^{[1
]}

机构：

[1] Def Res & Dev Estab, Vertox Lab, Gwalior, India

来源：

EUROPEAN JOURNAL OF MASS SPECTROMETRY | 2005年 / 11卷 / 03期

关键词：

chemical warfare agents; Chemical Weapons Convention; verification; Tabun; nerve agents; microsynthesis;

D O I：

10.1255/ejms.741

中图分类号：

O64 [物理化学（理论化学）、化学物理学]; O56 [分子物理学、原子物理学];

学科分类号：

070203 ; 070304 ; 081704 ; 1406 ;

摘要：

This communication describes the microsynthesis and gas chromatographic/mass spectrometric (GC/MS) analysis of O-alkyl N,N-dialkylphosphoramidocyanidates (ADAPCs), which are analogs of the chemical warfare agent, Tabun. The study was undertaken with a view to develop a spectral database of ADAPCs for verification purposes of the Chemical Weapons Convention (CWC). Reported microsynthetic approaches have advantages over traditional synthesis in terms of efficiency, synthetic waste and exposure to toxic chemicals. GC/MS analysis of a variety of these compounds (ADAPCs) was performed. Based on the obtained mass spectra of structurally diverse ADAPCs, the fragmentation routes are proposed, which explains most of the characteristic ions.

引用

页码：309 / 318

页数：10

共 19 条

[1]

Black R.M., 1996, CHEM ORGANOPHOSPHORU

[2] Derivatisation reactions in the chromatographic analysis of chemical warfare agents and their degradation products [J].