Androgen therapy improves insulin sensitivity and decreases leptin level in healthy adult men with low plasma total testosterone - A 3-month randomized placebo-controlled trial

被引：112

作者：

Simon, D

Charles, MA

Lahlou, N

Nahoul, K

Oppert, JM

Gouault-Heilmann, M

Lemort, N

Thibult, N

Joubert, E

Balkau, B

Eschwege, E

机构：

[1] Univ Paris 11, INSERM, U258, F-94807 Villejuif, France

[2] Univ Paris 11, INSERM, U21, F-94807 Villejuif, France

[3] Henri Mondor Hosp, Dept Endocrinol, Creteil, France

[4] St Vincent de Paul Hosp, Dept Hormonal Biochem, Paris, France

[5] Claude Levy Lab, Ivry, France

[6] Hop Hotel Dieu, Dept Nutr, Paris, France

[7] Henri Mondor Hosp, Dept Biol Hematol, Paris, France

[8] Univ Paris 12, INSERM, U468, Creteil, France

[9] Besins Iscovesco Labs, Paris, France

来源：

DIABETES CARE | 2001年 / 24卷 / 12期

关键词：

D O I：

10.2337/diacare.24.12.2149

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：2149 / 2151

页数：3

共 15 条

[1] Role of fatty acids in the pathogenesis of insulin resistance and NIDDM [J].

Boden, G .

DIABETES, 1997, 46 (01) :3-10

[2] Sex differences in the association of endogenous sex hormone levels and glucose tolerance status in older men and women [J].

Goodman-Gruen, D ;

Barrett-Connor, E .

DIABETES CARE, 2000, 23 (07) :912-918

[3] INSULIN-RESISTANCE, BODY-FAT DISTRIBUTION, AND SEX-HORMONES IN MEN [J].

HAFFNER, SM ;

KARHAPAA, P ;

MYKKANEN, L ;

LAAKSO, M .

DIABETES, 1994, 43 (02) :212-219

[4] Leptin concentrations, sex hormones, and cortisol in nondiabetic men [J].

Haffner, SM ;

Miettinen, H ;

Karhapaa, P ;

Mykkanen, L ;

Laakso, M .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1997, 82 (06) :1807-1809

[5] Reduced expression of the leptin gene (ob) by catecholamine through a G(s) protein-coupled pathway in 3T3-L1 adipocytes [J].

Kosaki, A ;

Yamada, K ;

Kuzuya, H .

DIABETES, 1996, 45 (12) :1744-1749

[6] Inverse correlation between serum testosterone and leptin in men [J].

Luukkaa, V ;

Pesonen, U ;

Huhtaniemi, I ;

Lehtonen, A ;

Tilvis, R ;

Tuomilehto, T ;

Koulu, M ;

Huupponen, R .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1998, 83 (09) :3243-3246

[7] ASSIMILATION AND MOBILIZATION OF TRIGLYCERIDES IN SUBCUTANEOUS ABDOMINAL AND FEMORAL ADIPOSE-TISSUE IN-VIVO IN MEN - EFFECTS OF ANDROGENS [J].

MARIN, P ;

ODEN, B ;

BJORNTORP, P .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1995, 80 (01) :239-243

[8]

MARIN P, 1992, INT J OBESITY, V16, P991

[9] Mental distress, obesity and body fat distribution in middle-aged men [J].

Rosmond, R ;

Lapidus, L ;

Marin, P ;

Bjorntorp, P .

OBESITY RESEARCH, 1996, 4 (03) :245-252

[10] INTERRELATION BETWEEN PLASMA TESTOSTERONE AND PLASMA-INSULIN IN HEALTHY ADULT MEN - THE TELECOM STUDY [J].

SIMON, D ;

PREZIOSI, P ;

BARRETTCONNOR, E ;

ROGER, M ;

SAINTPAUL, M ;

NAHOUL, K ;

PAPOZ, L .

DIABETOLOGIA, 1992, 35 (02) :173-177

← 1 2 →