How generalised are secondarily "generalised'' tonic-clonic seizures?

被引：43

作者：

Schindler, Kaspar ^{[1
]}

Leung, Howan ^{[1
]}

Lehnertz, Klaus ^{[1
]}

Elger, Christian E. ^{[1
]}

机构：

[1] Klin Epileptol, D-53105 Bonn, Germany

来源：

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY | 2007年 / 78卷 / 09期

关键词：

D O I：

10.1136/jnnp.2006.108753

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

In clinical practice, epileptic seizures with focal onset and subsequent generalised motor involvement are referred to as secondarily generalised seizures. The purpose of this study was to investigate the degree of electrophysiological generalisation in seizures that are clinically secondarily generalised. Intracranial EEG recordings of secondarily generalised tonic clonic seizures were visually and quantitatively analysed for the presence of epileptiform activity. In 24 ( 26%) of 93 seizures recorded from 17 ( 27%) of 64 patients, intracranial EEG channels were found that never recorded epileptiform activity during secondarily generalised tonic - clonic seizures. Our results demonstrate that seizures that are secondarily generalised clinically are not always generalised electrophysiologically. This may have therapeutic implications.

引用

页码：993 / 996

页数：4

共 9 条

[1]

Engel Jerome Jr., 1993, P609

[2]

Are "generalized" seizures truly generalized? Evidence of localized mesial frontal and frontopolar discharges in absence [J].