Modification of the pharmacokinetics of cyclosporine A and metabolites by the concomitant use of Neoral and diltiazem or ketoconazole in stable adult kidney transplants

被引：36

作者：

Foradori, A

Mezzano, S

Videla, C

Pefaur, J

Elberg, A

机构：

[1] Catholic Univ, Sch Med, Ctr Diagnost, Santiago, Chile

[2] Univ Austral Chile, Sch Med, Valdivia, Chile

[3] Univ Chile, Sch Med, Vina del Mar, Chile

[4] Univ Chile, Sch Med, Santiago, Chile

来源：

TRANSPLANTATION PROCEEDINGS | 1998年 / 30卷 / 05期

关键词：

D O I：

10.1016/S0041-1345(98)00393-5

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

引用

页码：1685 / 1687

页数：3

共 14 条

[1] Diltiazem increases blood concentrations of cyclized cyclosporine metabolites resulting in different cyclosporine metabolite patterns in stable male and female renal allograft recipients [J].

Bleck, JS ;

Thiesemann, C ;

Kliem, V ;

Christians, U ;

Hecker, H ;

Repp, H ;

Frei, U ;

WesthoffBleck, M ;

Manns, M ;

Sewing, KF .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1996, 41 (06) :551-556

[2] Clinically significant drug interactions with cyclosporin - An update [J].

Campana, C ;

Regazzi, MB ;

Buggia, I ;

Molinaro, M .

CLINICAL PHARMACOKINETICS, 1996, 30 (02) :141-179

[3] CONCOMITANT CYCLOSPORINE AND KETOCONAZOLE [J].

FREY, FJ .

LANCET, 1990, 335 (8681) :109-110

[4]

GAOTZE S, 1994, TRANSPLANT INT, V7, P157

[5] The use of other drugs to allow a lower dosage of cyclosporin to be used - Therapeutic and pharmacoeconomic considerations [J].

Jones, TE .

CLINICAL PHARMACOKINETICS, 1997, 32 (05) :357-367

[6]

NEUMAYER HH, 1992, KIDNEY INT S10, V56, P587

[7] A PRELIMINARY-REPORT OF DILTIAZEM AND KETOCONAZOLE - THEIR CYCLOSPORINE-SPARING EFFECT AND IMPACT ON TRANSPLANT OUTCOME [J].

PATTON, PR ;

BRUNSON, ME ;

PFAFF, WW ;

HOWARD, RJ ;

PETERSON, JC ;

RAMOS, EL ;

KARLIX, JL .

TRANSPLANTATION, 1994, 57 (06) :889-892

[8] DO CALCIUM-CHANNEL BLOCKERS HAVE RENAL PROTECTIVE EFFECTS [J].

REAMS, GP .

DRUGS & AGING, 1994, 5 (04) :263-287

[9]

SCHREIBER RA, 1996, HEPATOLOGY, V24, P304

[10]

Sharma A., 1996, Journal of the American Society of Nephrology, V7, P1923

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