Diffusion magnetic resonance imaging: A biomarker for treatment response in oncology

被引:257
作者
Hamstra, Daniel A.
Rehemtulla, Alnawaz
Ross, Brian D.
机构
[1] Univ Michigan, Med Ctr, Dept Radiat Oncol, Ann Arbor, MI 48109 USA
[2] Univ Michigan, Med Ctr, Dept Radiol, Ann Arbor, MI 48109 USA
[3] Univ Michigan, Med Ctr, Dept Biol Chem, Ann Arbor, MI 48109 USA
[4] Univ Michigan, Med Ctr, Ctr Mol Imaging, Ann Arbor, MI 48109 USA
关键词
D O I
10.1200/JCO.2007.11.9610
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Imaging of response to oncology treatments, either on clinical protocol or as part of standard practice, is a complicated process that has evolved during the last 10 years due to the improvement of existing imaging technologies and the introduction of newer modalities. Diffusion magnetic resonance imaging is a technique that measures the mobility of water within tissues and, as such, may function as a surrogate marker for both tissue cellularity and response to treatment that occur earlier than usual measures of tumor response. This review highlights the development of this technique and the state of current clinical understanding of its utility.
引用
收藏
页码:4104 / 4109
页数:6
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