Perspectives in diabetes - Genetic analysis of NIDDM - The study of quantitative traits

被引：90

作者：

Ghosh, S

Schork, NJ

机构：

[1] CASE WESTERN RESERVE UNIV, SCH MED, DEPT GENET, CLEVELAND, OH USA

[2] CASE WESTERN RESERVE UNIV, SCH MED, CTR HUMAN GENET, CLEVELAND, OH USA

[3] UNIV HOSP CLEVELAND, CLEVELAND, OH USA

来源：

DIABETES | 1996年 / 45卷 / 01期

关键词：

D O I：

10.2337/diabetes.45.1.1

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Many studies are in progress worldwide to elucidate the genetics of NIDDM. Nevertheless, few articles are available that combine the interdisciplinary fields of medicine, genetics, physiology, and statistics in order to provide the scientific rationale for such an endeavor, Here are describe the methodology and background necessary to study the genetics of NIDDM and discuss how to analyze the data, We also provide a detailed bibliography for researchers and a glossary for those who are not experts in the field. In particular, we wish to emphasize the analysis of intermediate quantitative traits as a means to dissect the genetic basis of NIDDM.

引用

页码：1 / 14

页数：14

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