Molecular imaging by cardiovascular MR

被引：19

作者：

Cyrus, Tillmann ^{[1
]}

Lanza, Gregory M. ^{[1
]}

Wickline, Samuel A. ^{[1
]}

机构：

[1] Washington Univ, Sch Med, Div Cardiol, St Louis, MO 63108 USA

来源：

JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE | 2007年 / 9卷 / 06期

关键词：

D O I：

10.1080/10976640701693766

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

Do molecularly-targeted contrast agents have what it takes to usher in a paradigm shift as to how we will image cardiovascular disease in the near future? Moreover, are non-invasive vulnerable plaque detection and preemptive treatments with these novel nanoparticulate agents within reach for clinical applications? In this article, we attempt to make a compelling case for how the advent of molecularly-targeted nanoparticle technology may change the way we detect atherosclerotic lesions, determine their clinical significance and even provide non-invasive treatments. Focusing on imaging with cardiovascular MR, an overview of the latest developments in this rapidly evolving field of so-called "intelligent" contrast agents that are able to interrogate the vascular wall and various complementary advanced imaging technologies are presented.

引用

页码：827 / 843

页数：17

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