CD40 and epithelial cells: across the great divide

被引：125

作者：

Young, LS ^{[1
]}

Eliopoulos, AG ^{[1
]}

Gallagher, NJ ^{[1
]}

Dawson, CW ^{[1
]}

机构：

[1] Univ Birmingham, Sch Med, CRC, Inst Canc Studies, Birmingham B15 2TA, W Midlands, England

来源：

IMMUNOLOGY TODAY | 1998年 / 19卷 / 11期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/S0167-5699(98)01340-1

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The widespread expression of CD40 in normal epithelial cells and carcinoma cells suggests that this receptor has important, additional influences beyond that of regulating immune responses. Here, Lawrence Young and colleagues discuss the effect of CD40 ligation on epithelial cells and consider the role of this pathway in the pathogenesis and treatment of carcinomas.

引用

页码：502 / 506

页数：5

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