Y2K+1 state-of-the-art on non-peptide phosphoantigens, a novel category of immunostimulatory molecules

被引：36

作者：

Espinosa, E

Belmant, C

Sicard, H

Poupot, R

Bonneville, M

Fournié, JJ

机构：

[1] CHU Purpan, INSERM U395, F-31024 Toulouse, France

[2] Innate Pharma, F-13009 Marseille, France

[3] Inst Biol, INSERM U463, F-44035 Nantes, France

来源：

MICROBES AND INFECTION | 2001年 / 3卷 / 08期

关键词：

pyrophosphate; antigens; gamma-delta lymphocytes; activation;

D O I：

10.1016/S1286-4579(01)01420-4

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Some human T cells are activated in vivo and in vitro by small non-peptide antigens, so-called phosphoantigens. Since their discovery in 1994, several reports have continuously documented novel members of this category of immunostimulatory molecules. This article reviews the current knowledge on their biochemical properties. (C) 2001 Editions scientifiques et medicales Elsevier SAS.

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收藏

页码：645 / 654

页数：10

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