Self-propelled particle model for cell-sorting phenomena

被引：96

作者：

Belmonte, Julio M. ^{[1
]}

Thomas, Gilberto L. ^{[1
]}

Brunnet, Leonardo G. ^{[1
]}

de Almeida, Rita M. C. ^{[1
]}

Chate, Hugues ^{[2
]}

机构：

[1] Univ Fed Rio Grande do Sul, Inst Fis, BR-91501970 Porto Alegre, RS, Brazil

[2] CEN Saclay, Serv Phys Etat Condense, F-91191 Gif Sur Yvette, France

来源：

PHYSICAL REVIEW LETTERS | 2008年 / 100卷 / 24期

关键词：

D O I：

10.1103/PhysRevLett.100.248702

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

A self-propelled particle model is introduced to study cell sorting occurring in some living organisms. This allows us to evaluate the influence of intrinsic cell motility separately from differential adhesion with fluctuations, a mechanism previously shown to be sufficient to explain a variety of cell rearrangement processes. We find that the tendency of cells to actively follow their neighbors greatly reduces segregation time scales. A finite-size analysis of the sorting process reveals clear algebraic growth laws as in physical phase-ordering processes, albeit with unusual scaling exponents.

引用

页数：4

共 38 条

[1] Cooperative self-organization of microorganisms
Ben-Jacob, E
Cohen, I
Levine, H
[J]. ADVANCES IN PHYSICS, 2000, 49 (04) : 395 - 554
[2] COOPERATIVE FORMATION OF CHIRAL PATTERNS DURING GROWTH OF BACTERIAL COLONIES
BENJACOB, E
COHEN, I
SHOCHET, O
TENENBAUM, A
VICSEK, T
CZIROK, A
[J]. PHYSICAL REVIEW LETTERS, 1995, 75 (15) : 2899 - 2902
[3] From snowflake formation to growth of bacterial colonies .2. Cooperative formation of complex colonial patterns
BenJacob, E
[J]. CONTEMPORARY PHYSICS, 1997, 38 (03) : 205 - 241
[4] Cell sorting is analogous to phase ordering in fluids
Beysens, DA
Forgacs, G
Glazier, JA
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (17) : 9467 - 9471
[5] Collective memory and spatial sorting in animal groups
Couzin, ID
Krause, J
James, R
Ruxton, GD
Franks, NR
[J]. JOURNAL OF THEORETICAL BIOLOGY, 2002, 218 (01) : 1 - 11
[6] Self-organization and collective behavior in vertebrates
Couzin, ID
Krause, J
[J]. ADVANCES IN THE STUDY OF BEHAVIOR, VOL 32, 2003, 32 : 1 - 75
[7] SCALING OF THE ACTIVE ZONE IN THE EDEN PROCESS ON PERCOLATION NETWORKS AND THE BALLISTIC DEPOSITION MODEL
FAMILY, F
VICSEK, T
[J]. JOURNAL OF PHYSICS A-MATHEMATICAL AND GENERAL, 1985, 18 (02): : L75 - L81
[8] SPINODAL DECOMPOSITION IN A TWO-DIMENSIONAL FLUID MODEL
FARRELL, JE
VALLS, OT
[J]. PHYSICAL REVIEW B, 1989, 40 (10): : 7027 - 7039
[9] LIQUID PROPERTIES OF EMBRYONIC-TISSUES - MEASUREMENT OF INTERFACIAL-TENSIONS
FOTY, RA
FORGACS, G
PFLEGER, CM
STEINBERG, MS
[J]. PHYSICAL REVIEW LETTERS, 1994, 72 (14) : 2298 - 2301
[10] SIMULATION OF THE DIFFERENTIAL ADHESION DRIVEN REARRANGEMENT OF BIOLOGICAL CELLS
GLAZIER, JA
GRANER, F
[J]. PHYSICAL REVIEW E, 1993, 47 (03): : 2128 - 2154

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