Large chiral discrimination of a molecular probe by bovine serum albumin

被引:34
作者
Kumar, CV [1 ]
Buranaprapuk, A [1 ]
Sze, HC [1 ]
机构
[1] Univ Connecticut, Dept Chem, Storrs, CT 06269 USA
关键词
D O I
10.1039/b007352k
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A phenylalanine-derived fluorescent probe shows high enantioselectivity for binding to bovine serum albumin; the L-isomer binds nearly one hundred times better than the D-isomer, which suggests the tight fitting of the L-isomer to the binding site.
引用
收藏
页码:297 / 298
页数:2
相关论文
共 23 条
[1]   Enantioselective binding sites on bovine serum albumin to dansyl amino acids [J].
Abe, Y ;
Fukui, S ;
Koshiji, Y ;
Kobayashi, M ;
Shoji, T ;
Sugata, S ;
Nishizawa, H ;
Suzuki, H ;
Iwata, I .
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY, 1999, 1433 (1-2) :188-197
[2]   SOME MECHANISTIC ASPECTS ON CHIRAL DISCRIMINATION OF ORGANIC-ACIDS BY IMMOBILIZED BOVINE SERUM-ALBUMIN (BSA) [J].
ALLENMARK, S ;
ANDERSSON, S .
CHIRALITY, 1992, 4 (01) :24-29
[3]   Substrate recognition and saturation kinetics in de novo designed histidine-based four-helix bundle catalysts [J].
Broo, KS ;
Nilsson, H ;
Nilsson, J ;
Baltzer, L .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1998, 120 (40) :10287-10295
[4]   Photochemical protein scissors: Role of aromatic residues on the binding affinity and photocleavage efficiency of pyrenyl peptides [J].
Buranaprapuk, A ;
Kumar, CV ;
Jockusch, S ;
Turro, NJ .
TETRAHEDRON, 2000, 56 (36) :7019-7025
[5]  
CSERHATI T, 1999, INT J BIOCHROMATOGR, V4, P203
[6]   Stereochemical resolution of racemates, in HPLC, using a chiral stationary phase based upon immobilized α-chymotrypsin.: I.: Structural chiral separations [J].
Félix, G ;
Descorps, V .
CHROMATOGRAPHIA, 1999, 49 (11-12) :595-605
[7]   Chiral separations of selected pharmaceuticals on avidin column [J].
Haque, A ;
Stewart, JT .
JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES, 1998, 21 (17) :2675-2687
[8]   Effect of surfactant agents and lipids on optical resolution of amino acid by ultrafiltration membranes containing bovine serum albumin [J].
Higuchi, A ;
Hashimoto, T ;
Yonehara, M ;
Kubota, N ;
Watanabe, K ;
Uemiya, S ;
Kojima, T ;
Hara, M .
JOURNAL OF MEMBRANE SCIENCE, 1997, 130 (1-2) :31-39
[9]   Chiral recognition of α-amino acids by charged cyclodextrins through cooperative effects of Coulomb interaction and inclusion [J].
Kitae, T ;
Nakayama, T ;
Kano, K .
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 1998, (02) :207-212
[10]   Photochemical protease: Site-specific photocleavage of hen egg lysozyme and bovine serum albumin [J].
Kumar, CV ;
Buranaprapuk, A ;
Opiteck, GJ ;
Moyer, MB ;
Jockusch, S ;
Turro, NJ .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (18) :10361-10366