Enantioselective hydrogenation catalyzed by highly active rhodium complexes of chiral phosphites with atropisomeric moieties

被引：30

作者：

Gergely, I

Hegedüs, C

Gulyás, H

Szöllosy, A

Monsees, A

Riermeier, T

Bakos, J ^{[1
]}

机构：

[1] Univ Veszprem, Dept Organ Chem, H-8201 Veszprem, Hungary

[2] Hungarian Acad Sci, Res Grp Petrochem, H-8201 Veszprem, Hungary

[3] Tech Univ Budapest, Dept Gen & Analyt Chem, H-1521 Budapest, Hungary

[4] Degussa AG, Projecthause Catalyse, D-65926 Frankfurt, Germany

来源：

TETRAHEDRON-ASYMMETRY | 2003年 / 14卷 / 09期

基金：

匈牙利科学研究基金会;

关键词：

D O I：

10.1016/S0957-4166(03)00131-9

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Excellent ee's and extremely high activities are obtained in the rhodium-catalyzed hydrogenation of dimethyl itaconate using simple and readily available H-8-BINOL based monodentate phosphites. The hydrogenation proceeds efficiently even at a substrate concentration of 5.263 mol L-1 and at a substrate to catalyst ratio (S/C) of 40,000 to give the product in 95.1% yield with up to 96.9% ee. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：1087 / 1090

页数：4

共 32 条

[1]

[Anonymous], ANGEW CHEM

[2] Asymmetric hydroformylation of styrene catalyzed by platinum complexes of chiral diphosphites with atropisomeric terminal moieties [J].