Mixed-element capture agents: A simple strategy for the construction of synthetic, high-affinity protein capture ligands

被引：18

作者：

Bachhawat-Sikder, K

Kodadek, T

机构：

[1] Univ Texas, SW Med Ctr, Ctr Biomed Invent, Dallas, TX 75390 USA

[2] Univ Texas, SW Med Ctr, Dept Internal Med, Dallas, TX 75390 USA

[3] Univ Texas, SW Med Ctr, Dept Mol Biol, Dallas, TX 75390 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2003年 / 125卷 / 32期

关键词：

D O I：

10.1021/ja034912n

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Demonstration of a simple strategy to generate synthetic high-affinity protein capture agents of practical utility for protein-detecting microarrays. The model study highlights capture of the MBP-Mdm2 fusion protein on a solid support by a linear sequence of peptides that bind to the two individual polypeptide chains. Copyright © 2003 American Chemical Society.

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收藏

页码：9550 / 9551

页数：2

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