Quantitative and selective assessment of sensory block during lumbar epidural anaesthesia with 1% or 2% lidocaine

被引:30
作者
Sakura, S [1 ]
Sumi, M [1 ]
Yamada, Y [1 ]
Saito, Y [1 ]
Kosaka, Y [1 ]
机构
[1] Shimane Med Univ, Dept Anaesthesiol, Izumo, Shimane 6938501, Japan
关键词
anaesthetic techniques; epidural; anaesthetics local; lidocaine; nerve; transmission;
D O I
10.1093/bja/81.5.718
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
We have examined sensory block during lumbar epidural anaesthesia using a cutaneous current perception threshold (CPT) sensory testing device in 20 patients who received 10 ml of either 1% or 2% lidocaine (lignocaine). CPT at 2000, 250 and 5 Hz stimulation at the trigeminal (V), ninth thoracic (T9) and second lumbar (L2) dermatomes, and dermatomal levels of block to light touch, temperature and pinprick discrimination were measured before and every 5 min until 60 min after epidural lidocaine. There were significant differences between 1% and 2% epidural lidocaine in all CPT at T9 and L2, in addition to maximal cephalad spread of the three sensory modalities. After 2% lidocaine, all CPT increased significantly at T9 and L2. In contrast, only at 250 and 5 Hz for L2 did epidural block with 1% lidocaine produce significant increases in CPT. Maximal level of loss of touch sensation after 1% lidocaine was significantly lower than that of cold and pinprick sensations. We conclude that the dose of lidocaine affected intensity of sensory block during lumbar epidural anaesthesia. In addition, differential neural block resulting from epidural anaesthesia appeared to be associated with a differential effect on nerve fibres of different sizes.
引用
收藏
页码:718 / 722
页数:5
相关论文
共 22 条
[1]   ZONES OF DIFFERENTIAL SENSORY BLOCK DURING EXTRADURAL ANESTHESIA [J].
BRULL, SJ ;
GREENE, NM .
BRITISH JOURNAL OF ANAESTHESIA, 1991, 66 (06) :651-655
[2]   MOLECULAR MECHANISMS OF LOCAL-ANESTHESIA - A REVIEW [J].
BUTTERWORTH, JF ;
STRICHARTZ, GR .
ANESTHESIOLOGY, 1990, 72 (04) :711-734
[3]  
CHADO HN, 1995, PAIN DIGEST, V5, P127
[4]   EXTRADURAL BLOCK WITH BUPIVACAINE - INFLUENCE OF DOSE, VOLUME, CONCENTRATION AND PATIENT CHARACTERISTICS [J].
DUGGAN, J ;
BOWLER, GMR ;
MCCLURE, JH ;
WILDSMITH, JAW .
BRITISH JOURNAL OF ANAESTHESIA, 1988, 61 (03) :324-331
[5]  
FINK BR, 1989, ANESTHESIOLOGY, V70, P851
[6]   MECHANISMS FOR DIFFERENTIAL BLOCK AMONG SINGLE MYELINATED AND NON-MYELINATED AXONS BY PROCAINE [J].
FRANZ, DN ;
PERRY, RS .
JOURNAL OF PHYSIOLOGY-LONDON, 1974, 236 (01) :193-210
[7]   DIFFERENTIAL SENSITIVITIES OF MAMMALIAN NERVE-FIBERS TO LOCAL-ANESTHETIC AGENTS [J].
GISSEN, AJ ;
COVINO, BG ;
GREGUS, J .
ANESTHESIOLOGY, 1980, 53 (06) :467-474
[8]   Differential nerve block - Direct measurements on individual myelinated and unmyelinated dorsal root axons [J].
Jaffe, RA ;
Rowe, MA .
ANESTHESIOLOGY, 1996, 84 (06) :1455-1464
[9]  
KATIMS JJ, 1986, APPL NEUROPHYSIOL, V49, P86
[10]   STEREOSELECTIVE INHIBITION OF NEURONAL SODIUM-CHANNELS BY LOCAL-ANESTHETICS - EVIDENCE FOR 2 SITES OF ACTION [J].
LEESON, S ;
WANG, GK ;
CONCUS, A ;
CRILL, E ;
STRICHARTZ, G .
ANESTHESIOLOGY, 1992, 77 (02) :324-335