Efficient and practical syntheses of three pentasaccharides core structures corresponding to N-glycans

被引：33

作者：

Du, YG ^{[1
]}

Zhang, MM ^{[1
]}

Kong, FZ ^{[1
]}

机构：

[1] Chinese Acad Sci, Ecoenvironm Sci Res Ctr, Beijing 100085, Peoples R China

来源：

TETRAHEDRON | 2001年 / 57卷 / 09期

基金：

中国国家自然科学基金;

关键词：

carbohydrates; glycosylations; glycopeptides;

D O I：

10.1016/S0040-4020(00)01161-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Three branched pentasaccharide derivatives and one tetrasaccharide were synthesized efficiently. The advantages of this method include a one-pot facile synthesis of 3,6-differentially protected mannose building block and an efficient strategy for oligosaccharide assembly. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：1757 / 1763

页数：7

共 24 条

[1] A simple synthesis of 8-(methoxycarbonyl)octyl 3,6-di-O-(α-D-mannopyranosyl)-α-D-mannopyranoside and derivatives and their use in the preparation of neoglycoconjugates [J].

Becker, B ;

Furneaux, RH ;

Reck, F ;

Zubkov, OA .

CARBOHYDRATE RESEARCH, 1999, 315 (1-2) :148-158

[2]

Dan A, 1998, CHEM-EUR J, V4, P2182, DOI 10.1002/(SICI)1521-3765(19981102)4:11<2182::AID-CHEM2182>3.3.CO

[3]

2-L

[4]

Depré D, 1999, CHEM-EUR J, V5, P3326

[5] Detritylation of mono- and di-saccharide derivatives using ferric chloride hydrate [J].

Ding, XL ;

Wang, W ;

Kong, FZ .

CARBOHYDRATE RESEARCH, 1997, 303 (04) :445-448

[6]

DU Y, Patent No. 001077236

[7]

Du YG, 2000, CARBOHYD RES, V323, P28

[8] Glycobiology: Toward understanding the function of sugars [J].

Dwek, RA .

CHEMICAL REVIEWS, 1996, 96 (02) :683-720

[9]

EISOKKARY SI, 1990, CARBOHYD RES, V203, P319

[10] SYNTHESIS OF METHYL 3-O-ALPHA-D-GALACTOPYRANOSYL-6-O-ALPHA-D-MANNOPYRANOSYL-ALPHA-D-MANNOPYRANOSIDE, METHYL 3-O-ALPHA-D-GLUCOPYRANOSYL-6-O-ALPHA-D-MANNOPYRANOSYL-ALPHA-D-MANNOPYRANOSIDE, METHYL 6-O-ALPHA-D-GALACTOPYRANOSYL-3-O-ALPHA-D-MANNOPYRANOSYL-ALPHA-D-MANNOPYRANOSIDE, AND METHYL 6-O-ALPHA-D-GLUCOPYRANOSYL-3-O-ALPHA-D-MANNOPYRANOSYL-ALPHA-D-MANNOPYRANOSIDE [J].

GAREGG, PJ ;

OSCARSON, S ;

TIDEN, AK .

CARBOHYDRATE RESEARCH, 1990, 203 (01) :C3-C8

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