Control of the β-hydride elimination making palladium-catalyzed coupling reactions more diversified

被引：82

作者：

Lu, XY ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organomet Chem, Shanghai 200032, Peoples R China

来源：

TOPICS IN CATALYSIS | 2005年 / 35卷 / 1-2期

基金：

中国国家自然科学基金;

关键词：

palladium(II)-catalyzed reactions; beta-hydride elimination; cross- coupling reactions; protonolysis; beta-heteroatom elimination;

D O I：

10.1007/s11244-005-3814-4

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Pd(II)-catalyzed coupling reactions were developed using beta-heteroatom elimination and protonolysis reaction to quench the carbon-palladium bond in the presence of halide ions or nitrogen ligands (pyridine, bipyridine, phenanthroline, etc.) for regenerating the divalent palladium species. Halide ions or nitrogen ligands are necessary for the catalytic cycle and high yield of the reactions. For Pd(0)-catalyzed reactions, control of beta-hydride elimination is also a challenge for making coupling reactions more diversified. Different kinds of ligands were used to make the coupling reaction suitable for aliphatic compounds. Recently, examples using chloride ion or bathophenanthroline for this purpose were also developed.

引用

页码：73 / 86

页数：14

共 111 条

[1] A palladium catalysed cyclisation-carbonylation of bromodienes:: control in carbonylation over facile β-hydride elimination [J].