Systemic reactions in US Marine Corps personnel who received Japanese encephalitis vaccine

被引：40

作者：

Berg, SW

Mitchell, BS

Hanson, RK

Olafson, RP

Williams, RP

Tueller, JE

Burton, RJ

Novak, DM

Tsai, TF

Wignall, FS

机构：

[1] USN,CTR ENVIRONM HLTH,NORFOLK,VA

[2] USN,ENVIRONM & PREVENT MED UNIT 6,HONOLULU,HI

[3] FIRST MARINE EXPEDITIONARY FORCE,CAMP PENDLETON,CA

[4] USN,AEROSP MED RES LAB,PENSACOLA,FL

[5] ARMED FORCES MED INTELLIGENCE CTR,FREDERICK,MD

[6] USN,ENVIRONM & PREVENT MED UNIT 5,SAN DIEGO,CA

[7] NEVADA CTY PUBL HLTH DEPT,NEVADA CITY,CA

[8] US ATLANTIC COMMAND,NORFOLK,VA

[9] AEA INT,FREEPORT,INDONESIA

[10] CTR DIS CONTROL & PREVENT,FT COLLINS,CO 80522

来源：

CLINICAL INFECTIOUS DISEASES | 1997年 / 24卷 / 02期

关键词：

D O I：

10.1093/clinids/24.2.265

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The overall hypersensitivity reaction rate among 14,249 U.S. Marine Corps personnel who received 36,850 doses of an investigational Japanese encephalitis vaccine was 10.3 per 10,000 doses; reaction rates were 16.1 and 10.3 per 10,000 doses for the first two doses, and 2.0 per 10,000 doses for the third, The reaction rate was 26.7 per 10,000 vaccinees, Of 38 reactors, 26 had urticaria and/or angioedema, and 11 had pruritus. Vaccine reaction intervals clustered within 48 hours for dose 1, but the median reaction interval for dose 2 was 96 hours, A history of urticaria or allergic rhinitis was associated with an increased probability of a vaccine reaction.

引用

页码：265 / 266

页数：2