Is apoptosis key in Alzheimer's disease?

被引：87

作者：

Barinaga, M

机构：

来源：

SCIENCE | 1998年 / 281卷 / 5381期

关键词：

D O I：

10.1126/science.281.5381.1303

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

收藏

页码：1303 / 1304

页数：2

相关论文

共 6 条

[1] Caspase inhibitor affords neuroprotection with delayed administration in a rat model of neonatal hypoxic-ischemic brain injury [J].

Cheng, Y ;

Deshmukh, M ;

D'Costa, A ;

Demaro, JA ;

Gidday, JM ;

Shah, A ;

Sun, YL ;

Jacquin, MF ;

Johnson, EM ;

Holtzman, DM .

JOURNAL OF CLINICAL INVESTIGATION, 1998, 101 (09) :1992-1999

[2] A POTENTIAL ROLE FOR APOPTOSIS IN NEURODEGENERATION AND ALZHEIMERS-DISEASE [J].

COTMAN, CW ;

ANDERSON, AJ .

MOLECULAR NEUROBIOLOGY, 1995, 10 (01) :19-45

[3] Inhibition of interleukin 1 beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage [J].

Hara, H ;

Friedlander, RM ;

Gagliardini, V ;

Ayata, C ;

Fink, K ;

Huang, ZH ;

ShimizuSasamata, M ;

Yuan, JY ;

Moskowitz, MA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (05) :2007-2012

[4] Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease [J].

Kim, TW ;

Pettingell, WH ;

Jung, YK ;

Kovacs, DM ;

Tanzi, RE .

SCIENCE, 1997, 277 (5324) :373-376

[5]

NAMURA S, 1998, J NEUROSCI, V18, P3569

[6] Inhibition of presenilin 1 expression is promoted by p53 and p21WAF-1 and results in apoptosis and tumor suppression [J].

Roperch, JP ;

Alvaro, V ;

Prieur, S ;

Tuynder, M ;

Nemani, M ;

Lethrosne, F ;

Piouffre, L ;

Gendron, MC ;

Israeli, D ;

Dausset, J ;

Oren, M ;

Amson, R ;

Telerman, A .

NATURE MEDICINE, 1998, 4 (07) :835-838