Protein kinase CK2: an enzyme that likes to be different

被引：8

作者：

Buchou, T ^{[1
]}

Cochet, C ^{[1
]}

机构：

[1] CEA Grenoble, Dept Reponse & Dynam Cellulaire, INSERM, EMI 104, F-38054 Grenoble 9, France

来源：

M S-MEDECINE SCIENCES | 2003年 / 19卷 / 6-7期

关键词：

D O I：

10.1051/medsci/20031967709

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Protein kinase CK2 (formerly known as casein kincise 2) was among the first protein kinases to be identified and characterized. Surprisingly, in spite of intense efforts, the regulation and cellular functions of CK2 remain obscure. However, recent data on its molecular structure, its signal-mediated intracellular dynamic localization and its unexpected function in cell survival have raised new interest in this enzyme. These studies reveal unique features of CK2 and highlight its importance in the transduction of survival signals.

引用

页码：709 / 716

页数：8

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