Electrical conduction through poly(dA)-poly(dT) and poly(dG)-poly(dC) DNA molecules

被引：442

作者：

Yoo, KH

Ha, DH

Lee, JO

Park, JW

Kim, J

Kim, JJ

Lee, HY

Kawai, T

Choi, HY

机构：

[1] Korea Res Inst Stand & Sci, Elect Devices Grp, Taejon 305600, South Korea

[2] Chonbuk Natl Univ, Dept Phys, Chonju 561756, South Korea

[3] Osaka Univ, Inst Sci & Ind Res, Osaka 5670047, Japan

[4] Sungkyunkwan Univ, Dept Phys, Suwon 440746, South Korea

来源：

PHYSICAL REVIEW LETTERS | 2001年 / 87卷 / 19期

关键词：

D O I：

10.1103/PhysRevLett.87.198102

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

We report direct measurements of electrical transport through poly(dA)-poly(dT) and poly(dG)-poly(dC) DNA molecules containing identical base pairs. The observed experimental results suggest that electrical transport through DNA molecules occurs by polaron hopping. We have also investigated the effect of gate voltage on the current-voltage curve. It demonstrates the possibility of a DNA field-effect transistor operating at room temperature. Moreover, the gate-voltage dependent transport measurements show that poly(dA)-poly(dT) behaves as an n-type semiconductor, whereas poly(dG)-poly(dC) behaves as a p-type semiconductor.

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页码：198102 / 1

页数：4

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