The Project Baseline Health Study: a step towards a broader mission to map human health

被引：45

作者：

Arges, Kristine ^{[1
]}

Assimes, Themistocles ^{[2
]}

Bajaj, Vikram ^{[2
]}

Balu, Suresh ^{[1
]}

Bashir, Mustafa R. ^{[1
]}

Beskow, Laura ^{[3
]}

Blanco, Rosalia ^{[1
]}

Califf, Robert ^{[4
]}

Campbell, Paul ^{[1
]}

Carin, Larry ^{[1
]}

Christian, Victoria ^{[1
]}

Cousins, Scott ^{[1
]}

Das, Millie ^{[2
]}

Dockery, Marie ^{[1
]}

Douglas, Pamela S. ^{[1
]}

Dunham, Ashley ^{[1
]}

Eckstrand, Julie ^{[1
]}

Fleischmann, Dominik ^{[2
]}

Ford, Emily ^{[1
]}

Fraulo, Elizabeth ^{[1
]}

French, John ^{[1
]}

Gambhir, Sanjiv S. ^{[2
]}

Ginsburg, Geoffrey S. ^{[1
]}

Green, Robert C. ^{[5
]}

Haddad, Francois ^{[2
]}

Hernandez, Adrian ^{[1
]}

Hernandez, John ^{[6
]}

Huang, Erich S. ^{[1
]}

Jaffe, Glenn ^{[1
]}

King, Daniel ^{[1
]}

Koweek, Lynne H. ^{[1
]}

Langlotz, Curtis ^{[2
]}

Liao, Yaping J. ^{[2
]}

Mahaffey, Kenneth W. ^{[2
]}

Marcom, Kelly ^{[1
]}

Marks, William J. ^{[2
,4
]}

Maron, David ^{[2
]}

McCabe, Reid ^{[1
]}

McCall, Shannon ^{[1
]}

McCue, Rebecca ^{[2
]}

Mega, Jessica ^{[4
]}

Miller, David ^{[4
]}

Muhlbaier, Lawrence H. ^{[1
]}

Munshi, Rajan ^{[2
]}

Newby, L. Kristin ^{[1
]}

Pak-Harvey, Ezra ^{[1
]}

Patrick-Lake, Bray ^{[1
]}

Pencina, Michael ^{[1
]}

Peterson, Eric D. ^{[1
]}

Rodriguez, Fatima ^{[2
]}

机构：

[1] Duke Univ, Sch Med, Durham, NC USA

[2] Stanford Univ, Sch Med, Stanford, CA 94305 USA

[3] Vanderbilt Univ, Sch Med, Nashville, TN 37212 USA

[4] Verily Inc, San Francisco, CA USA

[5] Harvard Univ, Sch Med, Boston, MA USA

[6] Google Inc, Mountain View, CA USA

[7] Calif Hlth & Longev Inst, Westlake Village, CA USA

来源：

NPJ DIGITAL MEDICINE | 2020年 / 3卷 / 01期

关键词：

DATA RESOURCE PROFILE; ROTTERDAM;

D O I：

10.1038/s41746-020-0290-y

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

The Project Baseline Health Study (PBHS) was launched to map human health through a comprehensive understanding of both the health of an individual and how it relates to the broader population. The study will contribute to the creation of a biomedical information system that accounts for the highly complex interplay of biological, behavioral, environmental, and social systems. The PBHS is a prospective, multicenter, longitudinal cohort study that aims to enroll thousands of participants with diverse backgrounds who are representative of the entire health spectrum. Enrolled participants will be evaluated serially using clinical, molecular, imaging, sensor, self-reported, behavioral, psychological, environmental, and other health-related measurements. An initial deeply phenotyped cohort will inform the development of a large, expanded virtual cohort. The PBHS will contribute to precision health and medicine by integrating state of the art testing, longitudinal monitoring and participant engagement, and by contributing to the development of an improved platform for data sharing and analysis.

引用

页数：10

共 38 条

[1] The "All of Us" Research Program [J].