Effects of 940 nm light-emitting diode (led) on sciatic nerve regeneration in rats

被引：23

作者：

Gaudens Serafim, Karla Guivernau ^{[1
]}

Ramos, Solange de Paula ^{[2
]}

de Lima, Franciele Mendes ^{[3
]}

Carandina, Marcelo ^{[1
]}

Ferrari, Osny ^{[2
]}

Lupiano Dias, Ivan Frederico ^{[3
]}

Toginho Filho, Dari de Oliveira ^{[3
]}

Cardoso Martins Siqueira, Claudia Patricia ^{[1
]}

机构：

[1] Univ Estadual Londrina, Dept Physiotherapy, Londrina, PR, Brazil

[2] Univ Estadual Londrina, Dept Histol, Londrina, PR, Brazil

[3] Univ Estadual Londrina, Dept Phys, Londrina, PR, Brazil

来源：

LASERS IN MEDICAL SCIENCE | 2012年 / 27卷 / 01期

关键词：

LED; Phototherapy; Nerve regeneration; LOW-LEVEL LASER; FUNCTIONAL RECOVERY; THERAPY LLLT; IRRADIATION; PHOTOTHERAPY; INDEX; MIGRATION; INJURY; REPAIR; ALPHA;

D O I：

10.1007/s10103-011-0923-0

中图分类号：

R318 [生物医学工程];

学科分类号：

100103 [病原生物学];

摘要：

The objective of the present study was to evaluate the effect of 940 nm wavelength light emitting diode (LED) phototherapy on nerve regeneration in rats. Forty male Wistar rats weighing approximately 300 g each were divided into four groups: control (C); control submitted to LED phototherapy (CLed); Sciatic Nerve Lesion without LED phototherapy (L); Sciatic Nerve Lesion with LED phototherapy (LLed). The lesion was caused by crushing the right sciatic nerve. A dose of 4 J/cm(2) was used for ten consecutive days beginning on the first postoperative day. Groups C and L were submitted to the same procedure as the LLed group, but the equipment was turned off. The LED phototherapy with 940 nm wavelength reduced the areas of edema, the number of mononuclear cells present in the inflammatory infiltration, and increased functional recovery scores at 7, 14 and 21 days. The results suggest that the use of phototherapy at 940 nm after nerve damage improves morphofunctional recovery and nerve regeneration.

引用

页码：113 / 119

页数：7

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