共 6 条
The origin of human chromosome 18 from a human/ape ancestor
被引:15
作者:
McConkey, EH
机构:
[1] Dept. Molec., Cell. Devmtl. Biol., University of Colorado, Boulder, CO
[2] Department of MCD Biology, Campus Box 347, University of Colorado, Boulder
来源:
CYTOGENETICS AND CELL GENETICS
|
1997年
/
76卷
/
3-4期
关键词:
D O I:
10.1159/000134546
中图分类号:
Q2 [细胞生物学];
学科分类号:
071009 ;
090102 ;
摘要:
Karyotype analysis by previous investigators demonstrated that human chromosome 18 differs from homologous chromosomes in the great apes by a pericentric inversion. The present study uses fluorescence in situ hybridization on human and pygmy chimpanzee chromosomes to confirm the inversion and to delimit the regions where the breakpoints must have occurred in the human/ape ancestor.
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页码:189 / 191
页数:3
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