Muscular mitochondrial dysfunction and type 2 diabetes mellitus

被引:52
作者
Schrauwen-Hinderling, Vera B.
Roden, Michael
Kooi, M. Eline
Hesselink, Matthijs K. C.
Schramen, Patrick
机构
[1] Maastricht Univ, Dept Human Biol, NUTRIM, NL-6200 MD Maastricht, Netherlands
[2] Maastricht Univ Hosp, Dept Radiol, Maastricht, Netherlands
[3] Med Univ Vienna, Acad Teaching Hosp, Hanusch Hosp, Dept Med 1, Vienna, Austria
关键词
insulin resistance; mitochondrial function; skeletal muscle; type; 2; diabetes;
D O I
10.1097/MCO.0b013e3282f0eca9
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Muscular mitochondrial aberrations in type 2 diabetes mellitus can be detected, but it is so far unclear if these aberrations are causally related to the development of the disease. Alternatively, mitochondrial,dysfunction may simply be the consequence of the elevated plasma fatty acids or glucose levels.
引用
收藏
页码:698 / 703
页数:6
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