Normal ranges for packed cell volume and hemoglobin concentration in adults: relevance to 'apparent polycythemia'

被引:47
作者
Fairbanks, VF
Tefferi, A
机构
[1] Mayo Clin & Mayo Fdn, Dept Med, Div Hematol, Rochester, MN 55905 USA
[2] Mayo Clin & Mayo Fdn, Dept Lab Med & Pathol, Rochester, MN 55905 USA
关键词
polycythemia; apparent polycythemia; hemoglobin concentration; hematocrit; packed cell;
D O I
10.1034/j.1600-0609.2000.065005285.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Published data from Europe and North America indicate that for non-iron-deficient adult Caucasian males, the normal mean packed cell volume (PCV) is 0.46 and the 2.5-97.5 percentile interval is 04.0-0.53. Corresponding values for adult Caucasian females are: mean PCV 0.42; 2.5-97.5 percentile interval 0.36-0.48. It is not usually appropriate to undertake studies of polycythemia in adult Caucasian males with PCV <0.55 (Hb Conc. <180 g/L) or in adult Caucasian females with PCV<0.50 (Hb Cone. <16.5 g/L). Application of this principle will reduce the number of inappropriate and costly studies that would otherwise be performed in patients whose PCV values are only in the upper percentiles of the normal range, and will help to avoid misdiagnoses and therapeutic misadventures.
引用
收藏
页码:285 / 296
页数:12
相关论文
共 39 条
[1]  
[Anonymous], 1995, BLOOD PRINCIPLES PRA
[2]  
[Anonymous], 1996, Blood: Textbook of hematology
[3]  
Beutler E., 1995, Williams hematology
[4]  
BICK RL, 1993, HEMATOLOGY CLIN LAB
[5]   RED CELL, PLASMA, AND BLOOD VOLUME IN HEALTHY WOMEN MEASURED BY RADICHROMIUM CELL-LABELING AND HEMATOCRIT [J].
BROWN, E ;
BRADLEY, B ;
WENNESLAND, R ;
HODGES, JL ;
HOPPER, J ;
YAMAUCHI, H .
JOURNAL OF CLINICAL INVESTIGATION, 1962, 41 (12) :2182-&
[6]   SPURIOUS (RELATIVE) POLYCYTHEMIA - NONEXISTENT DISEASE [J].
BROWN, SM ;
GILBERT, HS ;
KRAUSS, S ;
WASSERMAN, LR .
AMERICAN JOURNAL OF MEDICINE, 1971, 50 (02) :200-+
[7]  
Carneskog J, 1999, EUR J HAEMATOL, V62, P43
[8]   SOME VARIATIONS IN NORMAL HAEMOGLOBIN CONCENTRATION [J].
CRUICKSHANK, JM .
BRITISH JOURNAL OF HAEMATOLOGY, 1970, 18 (05) :523-+
[9]  
*E LIL CO, 1990, UNPUB ROUT LAB TESTS
[10]  
Fairbanks VIRGIL F., 2000, Hematology, V4, P381