Cardiovascular risk factors in primary care:: methods and baseline prevalence rates -: the DETECT program

被引:95
作者
Wittchen, HU
Glaesmer, H
März, W
Stalla, G
Lehnert, H
Zeiher, AM
Silber, S
Koch, U
Böhler, S
Pittrow, D
Ruf, G
机构
[1] Tech Univ Dresden, Inst Clin Psychol & Psychotherapy, Epidemiol & Hlth Serv Unit, D-01187 Dresden, Germany
[2] Max Planck Inst Psychiat, Munich, Germany
[3] Med Univ Graz, Inst Clin Chem, Graz, Austria
[4] Otto Von Guericke Univ, Dept Endocrinol & Metab Disorders, Magdeburg, Germany
[5] Goethe Univ Frankfurt, Dept Cardiol Nephrol, D-6000 Frankfurt, Germany
[6] Soc German Cardiol Private Med, Munich, Germany
[7] Univ Hamburg Hosp, Dept Med Psychol, D-2000 Hamburg, Germany
[8] Tech Univ Dresden, Inst Clin Pharmacol, D-8027 Dresden, Germany
[9] Pfizer GmbH, Clin Res, Karlsruhe, Germany
关键词
cardiovascular disease; coronary heart disease; diabetes; hypertension; lipid disorders; prevalence; risk factors;
D O I
10.1185/030079905X38187
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objectives: DETECT is an epidemiological study in primary care to examine (a) the prevalence rates and comorbidity of diabetes mellitus, hypertension, hyperlipidaemia and coronary heart disease (CHD), and associated conditions; (b) the frequency of behavioural and clinical risk factors for onset and progression; (c) the 12-month course and outcome; and (d) the met and unmet needs for these patients. Methods: Three-stage, cross-sectional clinical-epidemiological study with a prospective-longitudinal component in a nationally representative sample of N = 3795 primary care settings [response rate (RR): 60.2%] and N= 55 518 patients (RR: 95.5%). Patients completed a standardized assessment, including questionnaires for patients and the physician and diagnostic screening measures (i.e. blood pressure, heart rate, body mass index and waist circumference assessments). A subsample of patients (N = 7519) also completed a standardized laboratory screening program and was followed-up after 12 months. Data were weighted to adjust for non-response, regional distribution and attrition. Results: (1) Doctors and patients sample can be regarded as representative for primary care settings in Germany. (2) The clinician-rated point prevalence of hypertension is highest (35.5%), followed by hyperlipidaemia (29.1%), diabetes (14.1%) and CHD (12.1%); prevalence rates of each disorder as well as their co-incidence rates increase markedly with age. (3) The vast majority (78%) of all patients revealed multiple (3+) behavioural and clinical risk factors. Conclusion: The findings of DETECT underline the considerable burden for primary care doctors in managing a highly morbid patient population, with predominantly complex risk factor constellations, in routine care. Our data provide, in unprecedented detail, a basis for calculating age-, gender- and risk-group-adjusted risk-factor profiles in routine care.
引用
收藏
页码:619 / 629
页数:11
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