Status of genome and QTL mapping in pigs -: Data of Hohenheim F2 families

被引：30

作者：

Geldermann, H ^{[1
]}

Moser, G ^{[1
]}

Müller, E ^{[1
]}

Beeckmann, P ^{[1
]}

Yue, GH ^{[1
]}

Dragos, M ^{[1
]}

Bartenschlager, H ^{[1
]}

Cepica, S ^{[1
]}

Stratil, A ^{[1
]}

Schröffel, J ^{[1
]}

机构：

[1] Univ Hohenheim, Dept Anim Breeding & Biotechnol, Inst Anim Husb & Breeding, D-70593 Stuttgart, Germany

来源：

ARCHIV FUR TIERZUCHT-ARCHIVES OF ANIMAL BREEDING | 1999年 / 42卷 / 01期

关键词：

pig; linkage mapping; QTL mapping; performance traits;

D O I：

10.5194/aab-42-67-1999

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

Three informative F-2 families (by use of European Wild boar (W), Pietrain (P) and Meishan (M)), each with more than 300 animals, were genotyped for evenly spaced marker loci and recorded or more than 100 quantitative traits. Linkage and QTL mapping data for 8 chromosomes are presented (74, 76 and 75 mapped loci in families WxP, MxP and WxM, resp). Linkage maps gave evidence of heterogeneity in recombination between sexes and families. The male to female recombination ratio were 1.!9 (WxP), 1.35 (MxP) and 1.27 (WxM). Several QTLs were mapped for performance traits of growth, carcass and meat quality. These QTLs are located on different chromosomes and influenced by families. Larger effects were found on chromosome 6 and 7, and e.g. up to 60 % of the phenotypic F-2 variance for meat quality traits was associated with chromosome 6. Candidate genes are proposed for some of the QTL intervals. The subsequent QTL mapping use a combined strategy of genome-wide marker mapping with a positional candidate gene approach in order to identify genes which are significant for breeding.

引用

页码：67 / 81

页数：15

共 23 条

[1] GENETIC-MAPPING OF QUANTITATIVE TRAIT LOCI FOR GROWTH AND FATNESS IN PIGS [J].

ANDERSSON, L ;

HALEY, CS ;

ELLEGREN, H ;

KNOTT, SA ;

JOHANSSON, M ;

ANDERSSON, K ;

ANDERSSONEKLUND, L ;

EDFORSLILJA, I ;

FREDHOLM, M ;

HANSSON, I ;

HAKANSSON, J ;

LUNDSTROM, K .

SCIENCE, 1994, 263 (5154) :1771-1774

[2]

Andersson-Eklund L, 1998, J ANIM SCI, V76, P694

[3]

ARCHIBALD A, 1991, ANIML GENET S1, V23, P82

[4]

BEECKMANN P, 1998, THESIS U HOHENHEIM

[5]

CHURCHILL GA, 1994, GENETICS, V138, P963

[6] INVESTIGATIONS ON INHERITANCE OF QUANTITATIVE CHARACTERS IN ANIMALS BY GENE MARKERS .1. METHODS [J].

GELDERMANN, H .

THEORETICAL AND APPLIED GENETICS, 1975, 46 (07) :319-330

[7]

Green P., 1990, DOCUMENTATION CRIMAP

[8] STANDARD KARYOTYPE OF THE DOMESTIC PIG [J].

GUSTAVSSON, I .

HEREDITAS, 1988, 109 (02) :151-157

[9]

HALEY CS, 1994, GENETICS, V136, P1195

[10]

HARVEY WR, 1987, USERS GUIDE LSMLMW M

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