THROMBOSIS & HEMOSTASIS Coagulopathy in APL: a step forward?

被引：6

作者：

Avvisati, Giuseppe ^{[1
]}

机构：

[1] Univ Campus Biomed, Rome, Italy

来源：

BLOOD | 2012年 / 120卷 / 01期

关键词：

ACUTE PROMYELOCYTIC LEUKEMIA; TRANS-RETINOIC ACID; ANNEXIN-II;

D O I：

10.1182/blood-2012-05-427427

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Jacomo and colleagues advance our understanding of the coagulopathy present in acute promyelocytic leukemia (APL). By means of elegant and intriguing experiments performed in an APL mouse model, they demonstrate that supplementation with L-methionine, an essential amino acid that assists in the metabolism of homocysteine (Hcy), is able to prevent the fibrinolytic abnormalities present in this leukemia.(1)

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页码：4 / 6

页数：5

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