Pharmacology of the endothelinA receptor antagonist:: LU 135252

被引:10
作者
Rohmeiss, P
Birck, R
Braun, C
Münter, K
van der Woude, FJ
Kirchengast, M
机构
[1] Univ Heidelberg, Hosp Mannheim, Dept Med 5, D-68135 Mannheim, Germany
[2] Knoll AG, Expt & Cardiovasc Res, D-6700 Ludwigshafen, Germany
来源
CARDIOVASCULAR DRUG REVIEWS | 1998年 / 16卷 / 04期
关键词
endothelin; endothelin receptor antagonists; heart failure; LU; 135252; renal failure; vascular disease;
D O I
10.1111/j.1527-3466.1998.tb00365.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:391 / 412
页数:22
相关论文
共 85 条
[1]  
ALBERTS GF, 1994, J BIOL CHEM, V269, P10112
[2]  
AMANN K, 1998, UNPUB CIRCULATION
[3]   Differential modulation of the renal and myocardial endothelin system by angiotensin II in vivo -: Effects of chronic selective ETA receptor blockade [J].
Barton, M ;
Shaw, S ;
d'Uscio, LV ;
Moreau, P ;
Lüscher, TF .
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 1998, 31 :S265-S268
[4]   ETA receptor blockade prevents increased tissue endothelin-1, vascular hypertrophy, and endothelial dysfunction in salt-sensitive hypertension [J].
Barton, M ;
d'Uscio, LV ;
Shaw, S ;
Meyer, P ;
Moreau, P ;
Lüscher, TF .
HYPERTENSION, 1998, 31 (01) :499-504
[5]   Angiotensin II increases vascular and renal endothelin-1 and functional endothelin converting enzyme activity in vivo: Role of ETA receptors for endothelin regulation [J].
Barton, M ;
Shaw, S ;
dUscio, LV ;
Moreau, P ;
Luscher, TF .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1997, 238 (03) :861-865
[6]  
Barton M., 1998, European Heart Journal, V19, P13
[7]   Endothelin ETA receptor blockade restores NO-mediated endothelial function and inhibits atherosclerosis in apolipoprotein E-deficient mice [J].
Barton, M ;
Haudenschild, CC ;
D'Uscio, LV ;
Shaw, S ;
Münter, K ;
Lüscher, TF .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (24) :14367-14372
[8]  
BARTON M, 1998, UNPUB CIRC RES
[9]   Renoprotective effect of contemporary blocking of angiotensin II and endothelin-1 in rats with membranous nephropathy [J].
Benigni, A ;
Corna, D ;
Maffi, R ;
Benedetti, G ;
Zoja, C ;
Remuzzi, G .
KIDNEY INTERNATIONAL, 1998, 54 (02) :353-359
[10]  
BERTHOLD H, 1998, PFLUG ARCH EUR J PHY, V435, pR86