Oxidative aryl coupling reactions: a biomimetic approach to configurationally unstable or axially chiral biaryl natural products and related bioactive compounds

被引：105

作者：

Bringmann, G ^{[1
]}

Tasler, S ^{[1
]}

机构：

[1] Univ Wurzburg, Inst Organ Chem, D-97074 Wurzburg, Germany

来源：

TETRAHEDRON | 2001年 / 57卷 / 02期

关键词：

oxidative biaryl coupling; biphenyls; biscarbazoles; dimeric naphthylisoquinoline;

D O I：

10.1016/S0040-4020(00)00940-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Phenolic and non-phenolic oxidative aryl coupling reactions were successfully used in the efficient synthesis of diverse natural products and related compounds in the fields of biphenyls, biscarbazoles and bisnaphthylisoquinolines. For sterically more hindered biaryls, which consequently show the phenomenon of axial chirality, the products were prepared in an atropisomerically pure form. Their absolute axial configurations were assigned mainly by experimental and computational CD investigations. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：331 / 343

页数：13

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