Difficulties in stratifying neuropathic pain by mechanisms

被引:80
作者
Hansson, P [1 ]
机构
[1] Karolinska Inst Hosp, Dept Surg Sci, Sect Clin Pain Res, S-17176 Stockholm, Sweden
[2] Karolinska Inst Hosp, Ctr Multidisciplinary Pain, Neurogen Pain Unit, S-17176 Stockholm, Sweden
[3] Karolinska Inst Hosp, Dept Rehabil Med, S-17176 Stockholm, Sweden
关键词
neuropathic pain; animal models; behavioral testing; mechanism-based classification;
D O I
10.1016/S1090-3801(03)00051-X
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
The paper addresses issues related to the clinical relevance of currently employed animal models of neuropathic pain and our inability to translate clinical symptoms and signs into pathophysiological mechanisms. A machanism-based classification of pain is therefore currently not feasible. Suggestions on how to facilitate progress within this area are put forward. (C) 2003 European Federation of Chapters of the International Association for the Study of Pain. Published by Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:353 / 357
页数:5
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