Fat sites found!

被引：12

作者：

Cistola, DP ^{[1
]}

机构：

[1] Washington Univ, Sch Med, Dept Biochem & Mol Biophys, St Louis, MO 63110 USA

来源：

NATURE STRUCTURAL BIOLOGY | 1998年 / 5卷 / 09期

关键词：

D O I：

10.1038/1778

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Serum albumin is one of the most investigated proteins of the last half-century. Yet, the specific locations and three-dimensional features of its fatty acid binding sites have eluded definition. A new X-ray crystal structure of human serum albumin complexed with five molecules of myristate helps to solve the mystery.

引用

页码：751 / 753

页数：3

共 34 条

[1]

[Anonymous], 1982, LIPID PROTEIN INTERA

[2]

ASHBROOK JD, 1975, J BIOL CHEM, V250, P2333

[3]

BANASZAK L, 1994, ADV PROTEIN CHEM, V45, P89

[4] 3-DIMENSIONAL STRUCTURE OF HUMAN-SERUM ALBUMIN [J].

CARTER, DC ;

HE, XM ;

MUNSON, SH ;

TWIGG, PD ;

GERNERT, KM ;

BROOM, MB ;

MILLER, TY .

SCIENCE, 1989, 244 (4909) :1195-1198

[5] STRUCTURE OF HUMAN SERUM-ALBUMIN [J].

CARTER, DC ;

HE, XM .

SCIENCE, 1990, 249 (4966) :302-303

[6]

CISTOLA DP, 1987, J BIOL CHEM, V262, P10980

[7] PHASE-BEHAVIOR AND BILAYER PROPERTIES OF FATTY-ACIDS - HYDRATED 1-1 ACID SOAPS [J].

CISTOLA, DP ;

ATKINSON, D ;

HAMILTON, JA ;

SMALL, DM .

BIOCHEMISTRY, 1986, 25 (10) :2804-2812

[8] IONIZATION AND PHASE-BEHAVIOR OF FATTY-ACIDS IN WATER - APPLICATION OF THE GIBBS PHASE RULE [J].

CISTOLA, DP ;

HAMILTON, JA ;

JACKSON, D ;

SMALL, DM .

BIOCHEMISTRY, 1988, 27 (06) :1881-1888

[9]

CISTOLA DP, 1987, J BIOL CHEM, V262, P10971

[10] FATTY-ACID DISTRIBUTION IN SYSTEMS MODELING THE NORMAL AND DIABETIC HUMAN CIRCULATION - A C-13 NUCLEAR-MAGNETIC-RESONANCE STUDY [J].

CISTOLA, DP ;

SMALL, DM .

JOURNAL OF CLINICAL INVESTIGATION, 1991, 87 (04) :1431-1441

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