Addition of Bu3SnLi to tert-butanesulfinimines as an efficient route to chiral, nonracemic α-aminoorganostannanes

被引：57

作者：

Kells, KW ^{[1
]}

Chong, JM ^{[1
]}

机构：

[1] Univ Waterloo, Dept Chem, Guelph Waterloo Ctr Grad Work Chem & Biochem, Waterloo, ON N2L 3G1, Canada

来源：

ORGANIC LETTERS | 2003年 / 5卷 / 22期

关键词：

D O I：

10.1021/ol035702i

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Addition of Bu3SnLi to tert-butanesulfinimines proceeds with high diastereoselectivities to provide the expected adducts in excellent yields and typically with dr = >99:1. These adducts are readily converted to enantiomerically enriched N-Boc-protected alpha-aminoorganostannanes with complete retention of configuration.

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页码：4215 / 4218

页数：4

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