In vitro properties of gellan gum sponge as the dental filling to maintain alveolar space

被引：56

作者：

Chang, Shwu Jen ^{[2
]}

Huang, Yi-Ting ^{[1
]}

Yang, Shun-Chun ^{[1
,3
]}

Kuo, Shyh-Ming ^{[2
]}

Lee, Ming-Wei ^{[1
,3
]}

机构：

[1] Chung Shan Med Univ Hosp, Dept Clin Lab, Taichung, Taiwan

[2] I SHOU Univ, Dept Biomed Engn, Kaohsiung, Taiwan

[3] Chung Shan Med Univ Hosp, Sch Med Lab & Biotechnol, Taichung, Taiwan

来源：

CARBOHYDRATE POLYMERS | 2012年 / 88卷 / 02期

关键词：

Dental filling; Gellan gum; Teruplug((R)); BONE; SCAFFOLDS; TEETH; ACID;

D O I：

10.1016/j.carbpol.2012.01.017

中图分类号：

O69 [应用化学];

学科分类号：

070301 [无机化学];

摘要：

The insertion of dental filling into the dental cavity is a common method of maintaining the space and shape of dental cavities after dental extractions. To develop novel dental fillings meeting clinical requirements, gellan gum (GG) is selected in this study to prepare fillings with specific characteristics by modulating gellan gum concentrations (denoted as GG-DF). The results indicate that the microstructure, porosity, and compression modulus of 1.5% and 1.75% GG-DF are similar to a commercially product (Teruplug((R))) and with good blood absorption capacity. The degradation ratio of Teruplug((R)) in an amylase/phosphate buffer solution after 4 weeks is 80% whereas that of 1.5% and 1.75% GG-DF is 65%. Cell migration studies confirmed that the migration ability of fibroblast was significantly inhibited by gellan gum. These results demonstrate that 1.5% and 1.75% GG-DF are potentially viable for developing into dental fillings. Crown Copyright (c) 2012 Published by Elsevier Ltd. All rights reserved.

引用

页码：684 / 689

页数：6

共 20 条

[1]

Evaluation of mineral trioxide aggregate and calcium hydroxide cement as pulp-capping agents in human teeth [J].