Manganese Catalyzed α-Olefination of Nitriles by Primary Alcohols

被引：182

作者：

Chakraborty, Subrata ^{[1
]}

Das, Uttam Kumar ^{[1
]}

Ben-David, Yehoshoa ^{[1
]}

Milstein, David ^{[1
]}

机构：

[1] Weizmann Inst Sci, Dept Organ Chem, IL-76100 Rehovot, Israel

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2017年 / 139卷 / 34期

基金：

欧洲研究理事会; 以色列科学基金会;

关键词：

PNP PINCER COMPLEXES; ONE-POT SYNTHESIS; C BOND FORMATION; ALPHA; BETA-UNSATURATED NITRILES; HYDROGENATION CATALYSTS; CONDENSATION-REACTIONS; CARBONYL-COMPOUNDS; MICHAEL REACTIONS; ALKENYL NITRILES; IRON;

D O I：

10.1021/jacs.7b06993

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

Catalytic alpha-olefination of nitriles using primary alcohols, via dehydrogenative coupling of alcohols with nitriles, is presented. The reaction is catalyzed by a pincer complex of an earth-abundant metal (manganese), in the absence of any additives, base, or hydrogen acceptor, liberating dihydrogen and water as the only byproducts.

引用

收藏

页码：11710 / 11713

页数：4

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