2,15-dihydroxy-hexahelicene (HELIXOL): synthesis and use as an enantioselective fluorescent sensor

被引：173

作者：

Reetz, MT ^{[1
]}

Sostmann, S ^{[1
]}

机构：

[1] Max Planck Inst Kohlenforsch, D-45470 Mulheim, Germany

来源：

TETRAHEDRON | 2001年 / 57卷 / 13期

关键词：

enantioselection; fluorescence; helicenes; molecular recognition;

D O I：

10.1016/S0040-4020(01)00077-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The helical diol 2,15-dihydroxy-hexahelicene (HELIXOL) is an excellent fluorescence sensor for chiral amines and amino alcohols. The fluorescence of HELIXOL can be efficiently as well as enantioselectively quenched by the enantiomers of several chiral amines and amino alcohols. Its high fluorescence intensity and its ability to enantiodiscriminate effectively makes it potentially useful for high-throughput screening of ee. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：2515 / 2520

页数：6

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