Type 2 diabetes mellitus: a disease of the innate immune system? An update

被引：124

作者：

Crook, M ^{[1
]}

机构：

[1] Univ Hosp Lewisham, London SE13 6LH, England

来源：

DIABETIC MEDICINE | 2004年 / 21卷 / 03期

关键词：

acute phase response; complications; C-reactive protein; diabetes; inflammation; insulin resistance; sialic acid;

D O I：

10.1046/j.1464-5491.2003.01030.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A few years ago a hypothesis was proposed suggesting that elements of the innate immune system, such as acute phase reactants, contribute to the development of Type 2 diabetes mellitus. Acute phase reactants such as C-reactive protein and sialic acid may thus predict risk of developing Type 2 diabetes mellitus, as well as being markers of diabetes microvascular and macrovascular complications. This article discusses these issues.

引用

页码：203 / 207

页数：5

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