Bariatric Surgery in Patients with Cirrhosis and Portal Hypertension

被引:39
作者
Hanipah, Zubaidah Nor [1 ,2 ]
Punchai, Suriya [1 ,3 ]
McCullough, Arthur [4 ]
Dasarathy, Srinivasan [4 ]
Brethauer, Stacy A. [1 ]
Aminian, Ali [1 ]
Schauer, Philip R. [1 ]
机构
[1] Cleveland Clin, Bariatr & Metab Inst, Dept Gen Surg, M61,9500 Euclid Ave, Cleveland, OH 44195 USA
[2] Univ Putra Malaysia, Dept Surg, Fac Med & Hlth Sci, Serdang, Selangor, Malaysia
[3] Khon Kaen Univ, Dept Surg, Fac Med, Khon Kaen, Thailand
[4] Cleveland Clin, Pathobiol & Transplantat Ctr, Gastroenterol & Hepatol, Cleveland, OH 44106 USA
关键词
Bariatric surgery; Cirrhosis; Mortality; Morbidity; Portal hypertension; Sleeve gastrectomy; Gastric bypass; Risk factor; FATTY LIVER-DISEASE; OUTCOMES; THERAPY;
D O I
10.1007/s11695-018-3372-z
中图分类号
R61 [外科手术学];
学科分类号
100210 [外科学];
摘要
Studies on bariatric patients with cirrhosis and portal hypertension are limited. The aim of this study was to review our experience in cirrhotic patients with portal hypertension who had bariatric surgery. All cirrhotic patients with portal hypertension who underwent laparoscopic bariatric surgery, from 2007 to 2017, were retrospectively reviewed. Thirteen patients were included; eight (62%) were female. The median age was 54 years (interquartile range, IQR 49-60) and median BMI was 48 kg/m(2) (IQR 43-55). Portal hypertension was diagnosed based on endoscopy (n = 5), imaging studies (n = 3), intraoperative increased collateral circulation (n = 2), and endoscopy and imaging studies (n = 3). The bariatric procedures included sleeve gastrectomy (n = 10, 77%) and Roux-en-Y gastric bypass (n = 3, 23%). The median length of hospital stay was 3 days (IQR 2-4). Three 30-day complications occurred including wound infection (n = 1), intra-abdominal hematoma (n = 1), and subcutaneous hematoma (n = 1). No intraoperative or 30-day mortalities. There were 11 patients (85%) at 1-year follow-up and 9 patients (69%) at 2-year follow-up. At 2 years, the median percentage of excess weight loss (EWL) and total weight loss (TWL) were 49 and 25%, respectively. There was significant improvement in diabetes (100%), dyslipidemia (100%), and hypertension (50%) at 2 years after surgery. Bariatric surgery in selected cirrhotic patients with portal hypertension is relatively safe and effective.
引用
收藏
页码:3431 / 3438
页数:8
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