Cyclodextrins and emulsions

被引：79

作者：

Duchêne, D ^{[1
]}

Bochot, A ^{[1
]}

Yu, SC ^{[1
]}

Pépin, C ^{[1
]}

Seiller, M ^{[1
]}

机构：

[1] Univ Paris Sud, UMR 8612, CNRS, Fac Pharm, F-92290 Chatenay Malabry, France

来源：

INTERNATIONAL JOURNAL OF PHARMACEUTICS | 2003年 / 266卷 / 1-2期

关键词：

cyclodextrins; emulsions; multiple emulsions; fatty acids; glycerides;

D O I：

10.1016/S0378-5173(03)00384-3

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

This paper synthesises the literature on interactions between cyclodextrins (CD) and fatty acids and glycerides, and explains how these interactions allow the use of cyclodextrins to stabilise emulsions. An example of formulation with cyclodextrins is given which discusses the preparation of simple o/w emulsions, the addition of a model active ingredient, and the preparation of multiple emulsions in the absence of preformed surface active agents. (C) 2003 Published by Elsevier B.V.

引用

页码：85 / 90

页数：6

共 24 条

[1]

DUCHENE D, 1999, ACTIFS ADDITIFS COSM, P57

[2]

DUCHENE D, 1996, FORMES PHARM APPL LO, P480

[3]

Duchene D., 1987, CYCLODEXTRINS THEIR, P299

[4] COMPLEXATION OF CARBOXYLIC-ACIDS AND ANIONS BY ALPHA-CYCLODEXTRINS AND BETA-CYCLODEXTRINS [J].

GELB, RI ;

SCHWARTZ, LM .

JOURNAL OF INCLUSION PHENOMENA, 1989, 7 (04) :465-476

[5]

Grossiord J., 1998, MULTIPLE EMULSIONS S

[6]

JAEGERLEZER N, 1997, J CONTROL RELEASE, V45, P1

[7] NUCLEAR-MAGNETIC-RESONANCE STUDIES OF CYCLODEXTRIN COMPLEXES OF LINOLEIC-ACID AND ARACHIDONIC-ACID [J].

JYOTHIRMAYI, N ;

RAMADOSS, CS ;

DIVAKAR, S .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1991, 39 (12) :2123-2127

[8] Molecular dynamics simulation of cyclodextrin inclusion complexes in enzymatic lipid hydrolysis [J].

Kolossvary, GJ ;

Kolossvary, I .

BIOTECHNOLOGY LETTERS, 1996, 18 (04) :440-444

[9] INTERACTIONS BETWEEN BETA-CYCLODEXTRIN AND INSOLUBLE GLYCERIDE MONOMOLECULAR FILMS AT THE ARGON WATER INTERFACE - APPLICATION TO LIPASE KINETICS [J].

LAURENT, S ;

IVANOVA, MG ;

PIOCH, D ;

GRAILLE, J ;

VERGER, R .

CHEMISTRY AND PHYSICS OF LIPIDS, 1994, 70 (01) :35-42

[10]

LAURENT S, 1994, UNPUB CIRAD

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