CODE chemotherapy with and without granulocyte colony-stimulating factor in small-cell lung cancer

被引：39

作者：

Fukuoka, M ^{[1
]}

Masuda, N ^{[1
]}

Negoro, S ^{[1
]}

Matsui, K ^{[1
]}

Yana, T ^{[1
]}

Kudoh, S ^{[1
]}

Kusunoki, Y ^{[1
]}

Takada, M ^{[1
]}

Kawahara, M ^{[1
]}

Ogawara, N ^{[1
]}

Kodama, N ^{[1
]}

Kubota, K ^{[1
]}

Furuse, K ^{[1
]}

机构：

[1] NATL KINKI CENT HOSP CHEST DIS,DEPT INTERNAL MED,SAKAI,OSAKA 591,JAPAN

来源：

BRITISH JOURNAL OF CANCER | 1997年 / 75卷 / 02期

关键词：

extensive-stage small-cell lung cancer; recombinant human granulocyte colony-stimulating factor; CODE chemotherapy; dose intensity;

D O I：

10.1038/bjc.1997.50

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Sixty-three patients with extensive-stage small-cell lung cancer were randomized to receive either cyclophosphamide, vincristine, doxorubicin and etoposide (CODE) atone or CODE plus recombinant human granulocyte colony-stimulating factor (rhG-CSF). rhG-CSF administration in support of CODE chemotherapy resulted in increased mean total received dose intensity for all drugs (P = 0.03) with a significant improvement in survival (P = 0.004).

引用

页码：306 / 309

页数：4

共 21 条

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