The human physiome as an information environment

被引：7

作者：

Dao, N ^{[1
]}

McCormick, PJ ^{[1
]}

Dewey, CF ^{[1
]}

机构：

[1] MIT, Dept Mech Engn, Cambridge, MA 02139 USA

来源：

ANNALS OF BIOMEDICAL ENGINEERING | 2000年 / 28卷 / 08期

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

database; software component; XML; CORBA; biological informatics;

D O I：

10.1114/1.1315650

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 [生物医学工程];

摘要：

Modern biology is rapidly laying the foundation necessary for integrated modeling of physiological processes in living organisms. The human physiome project attempts to model interactions between biochemicals, cellular organelles, cells, tissues, and organs within whole organisms. One of the first challenges that this project faces is the development of a database environment flexible enough to accommodate the diversity in structure and content of physiological data. This paper reviews the current state of database technology, presents our understanding of the physiome database problem, and proposes a preliminary strategy for addressing it. (C) 2000 Biomedical Engineering Society. [S0090-6964(00)01008-0].

引用

页码：1032 / 1042

页数：11

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