Effect of infusing lactoferrin hydrolysate into bovine mammary glands with subclinical mastitis

被引:22
作者
Kawai, K
Nagahata, H
Lee, NY
Anri, A
Shimazaki, K
机构
[1] Tokachi AMAA, Chubu Vet Cli Ctr, Obihiro, Hokkaido, Japan
[2] Rakuno Gakuen Univ, Sch Vet Med, Ebutsu, Japan
[3] Hokkaido Univ, Grad Sch Agr, Dairy Sci Lab, Sapporo, Hokkaido 060, Japan
[4] Large Anim Clin & Res Ctr, Hokkaido, Japan
关键词
cow; lactoferrin; non-specific immunity; somatic cell counts; subclinical mastitis; treatment;
D O I
10.1023/A:1026039522286
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
The therapeutic effect of administering lactoferrin hydrolysate (LFH) into the mammary glands of cows with subclinical mastitis was evaluated. Seven millilitres of a preparation of LFH (7% protein) was infused into 35 quarters of 25 cows with subclinical mastitis. The numbers of bacteria in the milk from infected quarters decreased, and bacteria disappeared by the 14th day after the administration of LFH. The mean somatic cell counts (SCC) peaked one day after administration of LFH and the counts were significantly (p < 0.01) decreased on days 7, 14 and 21 compared to those before the administration of LFH. The mean lactoferrin concentration in the milk peaked on days 2 or 3 and then gradually decreased to day 14, returning to the level before the administration of LFH. It appears that administration of LFH may have a therapeutic effect when infused into the quarters of cows with subclinical mastitis.
引用
收藏
页码:539 / 548
页数:10
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