In vitro evaluation of terbinafine and itraconazole against dematiaceous fungi

被引:12
作者
McGinnis, MR
Pasarell, L
机构
[1] Univ Texas, Med Branch, Dept Pathol, Galveston, TX 77555 USA
[2] WHO, Collaborating Ctr Trop Dis, Galveston, TX USA
关键词
dematiaceous fungi; itraconazole; susceptibility testing; terbinafine;
D O I
10.1080/02681219880000371
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Two hundred and three isolates representing 15 species of filamentous ascomycetes were evaluated against terbinafine and itraconazole using a modification of the NCCLS M27-A standard reference method for yeasts. The MIC ranges and geometric means were similar, although terbinafine tended to have the lowest values. The loculoascomycete clade tested had consistently low MIC geometric mean values for its members, ranging from 0.03 to 0.17 mu g ml(-1) for terbinafine and 0.03-0.37 mu g ml(-1) for itraconazole.
引用
收藏
页码:243 / 246
页数:4
相关论文
共 16 条
  • [1] Oral terbinafine: A new antifungal agent
    AbdelRahman, SM
    Nahata, MC
    [J]. ANNALS OF PHARMACOTHERAPY, 1997, 31 (04) : 445 - 456
  • [2] CURVULARIA-LUNATA ENDOCARDITIS TREATED WITH TERBINAFINE - CASE-REPORT
    BRYAN, CS
    SMITH, CW
    BERG, DE
    KARP, RB
    [J]. CLINICAL INFECTIOUS DISEASES, 1993, 16 (01) : 30 - 32
  • [3] Clayton Y. M., 1987, Recent trends in the discovery, development and evaluation of antifungal agents., P433
  • [4] Treatment of chromomycosis with terbinafine: Preliminary results of an open pilot study
    Esterre, P
    Inzan, CK
    Ramarcel, ER
    Andriantsimahavandy, A
    Ratsioharana, M
    Pecarrere, JL
    Roig, P
    [J]. BRITISH JOURNAL OF DERMATOLOGY, 1996, 134 : 33 - 36
  • [5] Forty years of chromoblastomycosis in Madagascar: A review
    Esterre, P
    Andriantsimahavandy, A
    Ramarcel, ER
    Pecarrere, JL
    [J]. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1996, 55 (01) : 45 - 47
  • [6] ESTERRE P, 1997, REV CONTEMP PHARMACO, V8, P357
  • [7] GREER DL, 1994, INTRACONAZOLE MONOGR
  • [8] SUCCESSFUL TREATMENT OF CHROMOBLASTOMYCOSIS DUE TO FONSECAEA-PEDROSOI BY THE COMBINATION OF ITRACONAZOLE AND CRYOTHERAPY
    KULLAVANIJAYA, P
    ROJANAVANICH, V
    [J]. INTERNATIONAL JOURNAL OF DERMATOLOGY, 1995, 34 (11) : 804 - 807
  • [9] NAKA W, 1966, JPN J MED MYCOL, V37, P147
  • [10] NATIONAL COMMITTEE FOR CLINICAL LABORATORY STANDARDS-NCCLS, 1997, M27A NCCLS