Epithelial-to-Mesenchymal Transition in Liver Fibrosis: Dead or Alive?

被引：22

作者：

Popov, Yury ^{[1
]}

Schuppan, Detlef ^{[1
]}

机构：

[1] Harvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Div Gastroenterol & Hepatol, Boston, MA 02215 USA

来源：

GASTROENTEROLOGY | 2010年 / 139卷 / 03期

关键词：

EXPERIMENTAL BILIARY FIBROSIS; HEPATIC PROGENITOR CELLS; GROWTH-FACTOR; ANTIFIBROTIC THERAPIES; FIBROBLASTS DERIVE; DUCTULAR REACTION; RAT-LIVER; CHOLANGIOCYTES; HETEROGENEITY; HEPATOCYTES;

D O I：

10.1053/j.gastro.2010.07.015

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

引用

页码：722 / 725

页数：5

共 36 条

[1] Morphological, molecular, and functional heterogeneity of cholangiocytes from normal rat liver [J].

Alpini, G ;

Roberts, S ;

Kuntz, SM ;

Ueno, Y ;

Gubba, S ;

Podila, PV ;

LeSage, G ;

LaRusso, NF .

GASTROENTEROLOGY, 1996, 110 (05) :1636-1643

[2] Epithelial-to-Mesenchymal Transitions in the Liver [J].

Choi, Steve S. ;

Diehl, Anna Mae .

HEPATOLOGY, 2009, 50 (06) :2007-2013

[3] Fibrosis correlates with a ductular reaction in hepatitis C: Roles of impaired replication, progenitor cells and steatosis [J].

Clouston, AD ;

Powell, EE ;

Walsh, MJ ;

Richardson, MM ;

Demetris, AJ ;

Jonsson, JR .

HEPATOLOGY, 2005, 41 (04) :809-818

[4] HEPATIC HISTOLOGICAL-FINDINGS AFTER TRANSPLANTATION FOR CHRONIC HEPATITIS-B VIRUS-INFECTION, INCLUDING A UNIQUE PATTERN OF FIBROSING CHOLESTATIC HEPATITIS [J].

DAVIES, SE ;

PORTMANN, BC ;

OGRADY, JG ;

ALDIS, PM ;

CHAGGAR, K ;

ALEXANDER, GJM ;

WILLIAMS, R .

HEPATOLOGY, 1991, 13 (01) :150-157

[5] Broad-Spectrum Matrix Metalloproteinase Inhibition Curbs Inflammation and Liver Injury but Aggravates Experimental Liver Fibrosis in Mice [J].

de Meijer, Vincent E. ;

Sverdlov, Deanna Y. ;

Popov, Yury ;

Le, Hau D. ;

Meisel, Jonathan A. ;

Nose, Vania ;

Schuppan, Detlef ;

Puder, Mark .

PLOS ONE, 2010, 5 (06)

[6] Evidence for the epithelial to mesenchymal transition in biliary atresia fibrosis [J].

Diaz, Rosalyn ;

Kim, Ji Won ;

Hui, Jia-Ji ;

Li, Zhaodong ;

Swain, Gary P. ;

Fong, Keith S. K. ;

Csiszar, Katalin ;

Russo, Pierre A. ;

Rand, Elizabeth B. ;

Furth, Emma E. ;

Wells, Rebecca G. .

HUMAN PATHOLOGY, 2008, 39 (01) :102-115

[7]

DUFFIELD J, 2010, GASTROENTER IN PRESS

[8] Hepatic stellate cells: Protean, multifunctional, and enigmatic cells of the liver [J].

Friedman, Scott L. .

PHYSIOLOGICAL REVIEWS, 2008, 88 (01) :125-172

[9] Cholangiocyte proliferation and liver fibrosis [J].

Glaser, Shannon S. ;

Gaudio, Eugenio ;

Miller, Tim ;

Alvaro, Domenico ;

Alpini, Gianfranco .

EXPERT REVIEWS IN MOLECULAR MEDICINE, 2009, 11

[10]

Humphreys BD, AM J PATHOL, V176, P85

← 1 2 3 4 →