Genetics of glycopeptide resistance in Gram-positive pathogens

被引:37
作者
Courvalin, P [1 ]
机构
[1] Univ Calif San Diego, Dept Biol, La Jolla, CA 92093 USA
关键词
glycopeptides; vancomycin; teicoplanin; resistance; Enterococcus; Staphylococcus;
D O I
10.1016/j.ijmm.2004.10.002
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Glycopeptide resistance in enterococci, first detected in 1986, has since spread worldwide and represents a major health problem. Importantly, it has been recently acquired by Staphylococcus aureus. We shall review the genetics which accounts for this successful dissemination and discuss the possible origins of the resistance genes. (c) 2004 Elsevier GmbH. All rights reserved.
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页码:479 / 486
页数:8
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