Prevalences of type 2 diabetes, the insulin resistance syndrome, and coronary heart disease in an elderly, biethnic population

被引:56
作者
Lindeman, RD
Baumgartner, RN
Romero, LJ
Koehler, KM
Hundley, R
Schade, DS
Allen, AS
Garry, PJ
Liang, HC
机构
[1] Univ New Mexico, Sch Med, Dept Med, Albuquerque, NM 87131 USA
[2] Univ New Mexico, Sch Med, Dept Family & Community Med, Albuquerque, NM 87131 USA
[3] Univ New Mexico, Sch Med, Dept Pathol, Albuquerque, NM 87131 USA
关键词
D O I
10.2337/diacare.21.6.959
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
OBJECTIVE - To compare the prevalences of type 2 diabetes, the various cardiovascular risk factors encompassing the insulin resistance syndrome (IRS), and coronary heart disease (CHD) in elderly Hispanics compared with non-Hispanic whites. RESEARCH DESIGN AND METHODS - Elderly Hispanics (n = 414) and non-Hispanic whites (n = 469), randomly selected from the Medicare rolls of Bernalillo County (Albuquerque, NM; age greater than or equal to 65 years), underwent a home interview followed by an interview/examination by a nurse-practitioner, nurse, and nutritionist that included an evaluation of glucose tolerance. Prevalences of total and central obesity, dyslipidemia, hypertension, and microalbuminuria also were determined. History of myocardial infarction, recent angina, and/or coronary bypass graft, and electrocardiograms (ECGs) were used to document CHD. RESULTS-Elderly Hispanics had twice the prevalence of type 2 diabetes compared with non-Hispanic whites, but the prevalence of impaired glucose tolerance was not increased in Hispanics. Mean serum fasting and 2-h post-glucola insulin concentrations, fasting insulin resistance indexes, and HbA(1c) were higher in Hispanics. Hispanics were shorter, weighed less, and had more total body and central obesity The higher prevalences of dyslipidemia in Hispanics could be explained by a higher prevalence of diabetes. The prevalences of hypertension and CHD were not different for the mio ethnic groups. CONCLUSIONS - Elderly Hispanics had twice the prevalence of diabetes and higher prevalences of cardiovascular risk factors associated with IRS. Prevalences of hypertension and CHD were similar in the two ethnic groups.
引用
收藏
页码:959 / 966
页数:8
相关论文
共 45 条
[1]   BODY-FAT DISTRIBUTION, PLASMA-LIPIDS, AND LIPOPROTEINS [J].
ANDERSON, AJ ;
SOBOCINSKI, KA ;
FREEDMAN, DS ;
BARBORIAK, JJ ;
RIMM, AA ;
GRUCHOW, HW .
ARTERIOSCLEROSIS, 1988, 8 (01) :88-94
[2]   EXPLORATION OF SIMPLE INSULIN SENSITIVITY MEASURES DERIVED FROM FREQUENTLY SAMPLED INTRAVENOUS GLUCOSE-TOLERANCE (FSIGT) TESTS - THE INSULIN-RESISTANCE ATHEROSCLEROSIS STUDY [J].
ANDERSON, RL ;
HAMMAN, RF ;
SAVAGE, PJ ;
SAAD, MF ;
LAWS, A ;
KADES, WW ;
SANDS, RE ;
CEFALU, W .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 1995, 142 (07) :724-732
[3]   Epidemiology of sarcopenia among the elderly in New Mexico [J].
Baumgartner, RN ;
Koehler, KM ;
Gallagher, D ;
Romero, L ;
Heymsfield, SB ;
Ross, RR ;
Garry, PJ ;
Lindeman, RD .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 1998, 147 (08) :755-763
[4]   DIFFERENCES AT THE RECEPTOR AND POSTRECEPTOR LEVELS BETWEEN HUMAN OMENTAL AND SUBCUTANEOUS ADIPOSE-TISSUE IN THE ACTION OF INSULIN ON LIPOLYSIS [J].
BOLINDER, J ;
KAGER, L ;
OSTMAN, J ;
ARNER, P .
DIABETES, 1983, 32 (02) :117-123
[5]  
Boyko EJ, 1997, AM J EPIDEMIOL, V145, P18
[6]   Abdominal fat and insulin resistance in normal and overweight women - Direct measurements reveal a strong relationship in subjects at both low and high risk of NIDDM [J].
Carey, DG ;
Jenkins, AB ;
Campbell, LV ;
Freund, J ;
Chisholm, DJ .
DIABETES, 1996, 45 (05) :633-638
[7]   Non-insulin-dependent diabetes mellitus in minorities in the United States [J].
Carter, JS ;
Pugh, JA ;
Monterrosa, A .
ANNALS OF INTERNAL MEDICINE, 1996, 125 (03) :221-232
[8]   FIRI: A fair insulin resistance index? [J].
Cleland, SJ ;
Petrie, JR ;
Morris, AD ;
Ueda, S ;
Dorrian, CA ;
Connell, JMC .
LANCET, 1996, 347 (9003) :770-770
[9]   INSULIN RESISTANCE - A MULTIFACETED SYNDROME RESPONSIBLE FOR NIDDM, OBESITY, HYPERTENSION, DYSLIPIDEMIA, AND ATHEROSCLEROTIC CARDIOVASCULAR-DISEASE [J].
DEFRONZO, RA ;
FERRANNINI, E .
DIABETES CARE, 1991, 14 (03) :173-194
[10]  
DEFRONZO RA, 1979, AM J PHYSIOL, V237, pE214