Identification of candidates for epilepsy surgery in patients with tuberous sclerosis

被引:61
作者
Lachhwani, DK
Pestana, E
Gupta, A
Kotagal, P
Bingaman, W
Wyllie, E
机构
[1] Cleveland Clin Fdn, Sect Pediat Epilepsy & Pediat Neurol, Dept Neurol, Cleveland, OH 44195 USA
[2] Cleveland Clin Fdn, Dept Neurosurg, Cleveland, OH 44195 USA
关键词
D O I
10.1212/01.WNL.0000160389.93984.53
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The authors reviewed preoperative MRI and EEG findings in relation to postsurgical outcome in 17 patients with refractory epilepsy due to tuberous sclerosis complex (TSC). Resecting concordant MRI ( main tuber) and EEG abnormalities offered seizure freedom (8/9, 89%; median follow-up 25 months) comparable to other focal etiologies. Patients with nonconcordant MRI and EEG findings did less well (3/8, 38%, seizure free; p = 0.027, OR = 13).
引用
收藏
页码:1651 / 1654
页数:4
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